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Los Angeles Southern California (LASC)




The Los Angeles-Southern California Regional Clinical Coordinating Center for the NINDS Stroke Clinical Trials Network (LASC StrokeNet) is a consortium of 49 acute stroke and rehabilitation medical centers in Los Angeles and Orange Counties, coordinated jointly by three academic medical centers, UCLA (co-lead), USC (co-lead), and UC Irvine. In the LASC StrokeNet, physicians, nurses, and coordinators from multiple specialties, including neurology, neurosurgery, neuroradiology, rehabilitation medicine, and emergency medicine, work collaboratively to advance develop new therapies and diagnostic approaches for neurovascular disease.

 The LASC StrokeNet’s aims are:
1) perform high quality NINDS Stroke Clinical Trial (NSTN) acute and prevention trials throughout Los Angeles and Orange County
2) perform high quality NSTN recovery and rehabilitation trials throughout Los Angeles and Orange County
3) ensure participation of high volumes of underserved populations in NSTN trials, including women, Hispanic-American, African-American, and other minority populations
4) educate fellows, residents, medical students, premedical students, and junior faculty to engage in stroke translational research..

Addressing population diversity and health disparities is a special focus of LASC StrokeNet. Rates in LA and OC of premature death and disability due to stroke exceed national averages. Stroke is the 2nd leading cause of death in LA County and 3rd leading cause of death in OC. Because current therapeutic options inadequately prevent stroke morbidity in our diverse race-ethnic population, we pursue a regionally transformative mission. Moreover, as the national U.S. population becomes more diverse - more like LA and OC - in the 21st century, our contributions to stroke prevention, acute treatment, and recovery research may offer a model for translational research implementation nationwide.


Co-Principal Investigator 
Jeffrey Saver, MD Director, UCLA Comprehensive Stroke Center
UCLA Comprehensive Stroke Center
710 Westwood Plaza
Los Angeles, CA 90095

Areas of Interest: Novel stroke acute and prevention treatments, clinical trial design, new diagnostic modalities in cerebrovascular disease.

Co-Principal Investigator

Gene Sung, MD Chief of the Division of Stroke and Neurocritical Care, USC
Neurology Department
1100 N. State St, Clinic Tower A4E111
Los Angeles, CA 90033

Areas of Interest: Critical care management of acute brain injury, acute stroke therapy, stroke prevention and rehabilitation.

Clinical Coordinators

Ileana Grunberg, RN
Clare Binley, RN Research Coordinator

Affiliated Satellite Performance sites:
• Antelope Valley Hospital • UCS Arcadia Hospital • Cedars Sinai Medical Center • Emanate Health Queen of the Valley Hospital • Fountain Valley RMC • Garfield MC • Glendale Adventist MC • Greater VA Los Angeles • Henry Mayo Newhall Memorial Hospital • Hoag Memorial Hospital Presbyterian • Hollywood Presbyterian MC • Huntington Memorial MC • Kaiser: Baldwin Park MC • Kaiser: Los Angeles MC • Kaiser: Woodland Hills • LA County Harbor- UCLA MC • LA County Olive View- UCLA MC • LA County Rancho Los Amigos • Los Angeles General Medical Center• Lakewood Regional MC • Long Beach Memorial MC • Los Alamitos MC • Los Robles Hospital & MC • Mission Hospital Regional MC • National Rehab Center • Northridge Hospital & MC • Pomona Valley Hospital MC • Presbyterian Intercommunity Hospital • Providence Holy Cross MC • Providence Little Company of Mary MC- San Pedro • Providence Little Company of Mary MC- Torrance • Providence Saint Joseph MC • Providence Tarzana MC • Saddleback Memorial MC • Saint Joseph MC • Saint Jude MC • Saint Mary MC • Torrance Memorial MC • UC Irvine MC • UCLA Ronald Reagan MC • UCLA Santa Monica MC • University of New Mexico USC Keck Hospital • Valley Presbyterian Hospital • Verdugo Hills Hospital • West Hills Hospital & MC • Western Medical Center • White Memorial Medical Center, Good Samaritan Hospital
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