The NIH has created the NIH StrokeNet to conduct small and large clinical trials and research studies to advance acute stroke treatment, stroke prevention, and recovery and rehabilitation following a stroke. This network of 25 regional centers across the U.S., which involves more than 200 hospitals, is designed to serve as the infrastructure and pipeline for exciting new potential treatments for patients with stroke and those at risk for stroke. In addition, NIH StrokeNet will provide an educational platform for stroke physicians and clinical trial coordinators.
In September 2013, the National Institutes of Health funded the stroke trials network, NIH StrokeNet. The StrokeNet infrastructure consists of 25 regional coordinating centers across the US, a national coordinating center at the University of Cincinnati, and a national data management center (Medical University of South Carolina). The primary goal of this network is to maximize efficiencies to develop, promote and conduct high-quality, multi-site clinical trials focused on key interventions in stroke prevention, treatment and recovery.
NIH is soliciting for Pain Research Centers to join a clinical trial network. NIH has mounted a major effort to improve pain management as a part of its response to the opioid crisis in America. One cornerstone of that effort is an phase 2 clinical trial network to test new, non-addictive pain therapies in well-phenotyped patients. This is part of a public-private partnership with academia, pharmaceutical companies, biotechnology and device companies. The initial call did not get the number of needed participating sites and the call is now out for a second and final time. Please consider applying to join what will be an innovative, and very exciting project. To learn more see
Thought leaders in this emerging field will convene over the course
of one week to share ideas, learn and create pathways to deliver
cutting edge care to pediatric and young adult cerebrovascular
and stroke patients.
Major Topic Areas -
• Endovascular Management Options for Acute Stroke
• Hemorrhagic Stroke (Cerebral Aneurysms, AVMs,
Moyamoya, Cardioembolic, and Vasospasm)
• Sickle Cell Related Cerebrovascular Complications
• Cerebral Arteriopathy and Acute Stroke Mimics
• Cerebral Venopathy
The conference format includes didactic lectures and case
presentations held each morning; there is ample time for
discussion and audience participation.
The Distinguished Clinical Research Achievement Awards are presented to the top two studies that show creativity, innovation, or a novel approach that demonstrates an immediate impact on the health and well-being of patients. This means we were ranked #2 or #3 among all clinical trials performed last year— includes all areas of medicine. The #1 award went to a study that reduced HTN by instituting therapy though a network of black barbershops
DEFUSE 3 results will be presented to selected members of Congress March 7th.
REGISTER TODAY! MAY 15-17, 2019
BALTIMORE - at the RENAISSANCE BALTIMORE HARBORPLACE HOTEL
If you are new to working with NIH grants and ready to learn, engage and connect with others who are eager to gain a better understanding of NIH grant policies and processes…then register today for the Spring 2019 NIH Regional Seminar on Program Funding and Grants Administration! What can you expect?
We are recruiting for our next cohort of scholars. We have a two-stage application process. The next deadline for brief preliminary applications is November 15, 2018. For details, see https://rehabmedicine.georgetown.edu/K12-webpage
The Neurorehabilitation and Restorative Neuroscience Training Network (NRNTN) provides outstanding research training and mentorship for clinical scholars in Neurorehabilitation and prepares rehabilitation clinician investigators for sustained and productive academic careers in Neurorehabilitation. NRNTN is funded by the National Center for Medical Rehabilitation Research, NIH/NICHD.
Interested in expanding your clinical research knowledge base? Registration for the 2018-2019 NIH Introduction to the Principles and Practice of Clinical Research (IPPCR) course is now open!
This free, self-paced online course runs from October 1, 2018 to June 30, 2019. Graduate students, post-doctoral scholars, medical, dental, and pharmacy students, scientists, nurses, and other health professionals are encouraged to enroll now.
The purpose of this funding opportunity announcement (FOA) issued by NINDS is to invite applications for the Coordinating Center (CC) for the NIH Stroke Preclinical Assessment Network (SPAN). SPAN will facilitate testing of up to 6 promising neuroprotective drugs or interventions to be given prior to or at the time of reperfusion in experimental models of ischemic stroke (e.g., transient middle cerebral artery occlusion). The CC will work with the awarded network sites (RFA-NS-18-033) and will provide centralized administrative oversight and coordination of all aspects of the network.
The purpose of this funding opportunity announcement (FOA) issued by NINDS is to invite applications for network sites for the NIH Stroke Preclinical Assessment Network (SPAN). SPAN will facilitate testing of up to 6 promising neuroprotective drugs or interventions to be given prior to or at the time of reperfusion in experimental models of ischemic stroke (e.g., transient middle cerebral artery occlusion). The awarded network sites will become part of the network and will collaborate with the other awarded sites under the oversight and central coordination provided by the SPAN Coordinating Center (RFA-NS-18-034).
May 24, 2018 -
In-home rehabilitation, using a telehealth system and supervised by licensed occupational/physical therapists, is an effective means of improving arm motor status in stroke survivors, according to findings presented by University of California, Irvine neurologist Steven C. Cramer, MD, at the recent 2018 European Stroke Organisation Conference in Gothenburg, Sweden.
Advances in brain imaging can identify a greater number of stroke patients who can receive therapy later than previously believed, according to a new study co-led by researchers in NIH StrokeNet. The results of the "Endovascular Therapy Following Imaging Evaluation for the Ischemic Stroke (DEFUSE 3)” trial, presented at the International Stroke Conference 2018 in Los Angeles and published on Jan. 24 in the New England Journal of Medicine, demonstrated that physically removing brain clots up to 16 hours after symptom onset in selected patients led to improved outcomes compared to standard medical therapy. Click Full Story to see the published article:
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U01)
This FOA encourages applications for multi-site exploratory and confirmatory clinical trials focused on promising interventions, as well as biomarker-or outcome measure validation studies that are immediately preparatory to trials in stroke prevention, treatment, and recovery. Successful applicants will collaborate and conduct the trial within the NIH StrokeNet. Following peer review, NINDS will prioritize trials among the highest scoring to be conducted in the NIH StrokeNet infrastructure.
NIH StrokeNet Small Business Innovation Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U44)
This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose exploratory and confirmatory clinical trials focused on promising interventions, as well as biomarker-or outcome measure validation studies that are immediately preparatory to trials in stroke prevention, treatment, and recovery. The program will utilize the cooperative agreement mechanism to enable milestone-drive projects.
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke
Treatment, Recovery, and Prevention Infrastructure Resource
This FOA encourages requests for access to research resources for multi-site exploratory and confirmatory clinical trials focused on promising interventions, as well as biomarker-or outcome measure validation studies that are immediately preparatory to trials in stroke prevention, treatment, and recovery. Successful applicants will be given access to the NIH StrokeNet infrastructure.
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NIH StrokeNet Education “Pathophysiological Links between Migraine and Stroke”; Presented by Cenk Ayata, MD, Harvard Medical School, Massachusetts General Hospital NIH StrokeNet Education “Pathophysiological Links between Migraine and Stroke”; Presented by Cenk Ayata, MD, Harvard Medical School, Massachusetts General HospitalNIH StrokeNet Education “Pathophysiological Links between Migraine and Stroke.
Treatments for acute stroke include IV t-PA, stroke centers, stroke units, endovascular thrombectomy devices for selected patients, nimodipine for subarachnoid hemorrhage, and aneurysm coiling and clipping for ruptured aneurysms. Intracerebral hemorrhage has proven to be the most challenging for effective treatments; however recent research has shown promise
Despite the advances made in acute stroke care, stroke remains the leading cause of adult disability in Americans. World-wide there is an estimated 50 million stroke survivors coping with significant physical, cognitive and emotional deficits. The field of stroke recovery and restorative neuroscience is still young and provides a rich environment for innovative trials.