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NIH has created the NIH StrokeNet to conduct small and large clinical trials and research studies to advance acute stroke treatment, stroke prevention, and recovery and rehabilitation following a stroke across the lifespan. This network of 27 regional centers across the U.S., which involves approximately 500 hospitals in the U.S., is designed to serve as the infrastructure and pipeline for exciting new potential treatments for patients with stroke and those at risk for stroke. The StrokeNet trials also collaborate with sites in other countries including Canada, Germany, United Kingdom, Spain, and Japan. In addition, NIH StrokeNet will provide an educational platform for stroke physicians, clinical trial coordinators and stroke researchers.

Working with StrokeNet is a cooperative venture between NINDS, the StrokeNet network, and the applicant. Potential applicants for funding including academic investigators, advocacy groups/foundations, small businesses and the pharmaceutical industry are welcomed. You DO NOT need to be part of the StrokeNet infrastructure to apply to conduct a study within the network.

To apply for NINDS funding potential applicants should contact NINDS Office of Clinical Research in order to discuss the feasibility of conducting the proposed trial through the StrokeNet infrastructure. Please refer to the documents tab on the StrokeNet website for the full process for solicitation and review of Clinical Trials for NIH StrokeNet and the NIH StrokeNet Concept Synopsis.

Referral/Review Process for StrokeNet Applications

  • Prospective applicant contacts NINDS/OCR to discuss the proposed trial concept proposal (email
  • NINDS program staff will discuss the proposed project proposal and determine its fit with NINDS mission and priorities
  • Projects that have good NINDS support are referred to are referred to one of the three StrokeNet working groups (Prevention, Treatment, or Recovery) for further refinement of the concept proposal and eventual assessment of feasibility.
  • Prospective applicants whose projects have support from NINDS program staff and are judged to be feasible for network performance must submit a formal application in response to one of the StrokeNet FOAs (also located under documents) for peer review and subsequent consideration by the NINDS Advisory Council.

We look forward to partnering with our colleagues in other NIH-funded networks, stroke networks in other countries, national organizations focused on stroke, industry, and most of all patients who have suffered a stroke, so we can decrease the burden of this devastating disease.  We appreciate your interest and welcome your participation. Welcome to StrokeNet!

Joseph P Broderick, MD & Pooja Khatri, MD
Co-Principal Investigators
National Coordinating Center 

Jordan Elm, PhD, Wenle Zhao, PhD & Catherine Dillion, MS
Co-Principal Investigators
National Data Management Center