Primary and Secondary prevention of stroke is a primary public health concern as approximately 795,000 people in the United States experience a new or recurrent stroke. Efforts in controlling risk factor such as hypertension, diabetes mellitus control, dyslipidemia treatment and smoking cessations programs have had an impact on stroke mortality over the last decade. However stroke remains a leading cause of serious long-term disability in the United States.
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Treatments for acute stroke include IV t-PA, stroke centers, stroke units, endovascular thrombectomy devices for selected patients, nimodipine for subarachnoid hemorrhage, and aneurysm coiling and clipping for ruptured aneurysms. Intracerebral hemorrhage has proven to be the most challenging for effective treatments; however recent research has shown promise.
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Despite the advances made in acute stroke care, stroke remains the leading cause of adult disability in Americans. World-wide there is an estimated 50 million stroke survivors coping with significant physical, cognitive and emotional deficits. The field of stroke recovery and restorative neuroscience is still young and provides a rich environment for innovative trials.